News and Publications

CAP Articles - 2024 Block 1

Prior Blocks

• CAP Articles - 2023 Block 2

  Head/Neck

  • Anesi SD, et al. Lirentelimab for severe and chronic forms of allergic conjunctivitis. Journal of Allergy and Clinical Immunology.
  • Bachert C. Efficacy and safety of benralizumab in chronic rhinosinusitis with nasal polyps: A randomized, placebo-controlled trial. Journal of Allergy and Clinical Immunology.
  • Fokkens WJ, et al. A comparison of international guidelines for Rhinosinusitis. The Journal of Allergy and Clinical Immunology: In Practice.
  • Peters AT, et al. Prevalence of bronchiectasis in patients with chronic rhinosinusitis in a tertiary care center. The Journal of Allergy and Clinical Immunology: In Practice.

  Dermatologic

  • DeKoven JG, et al. Occupational contact dermatitis: Retrospective analysis of North American contact dermatitis group data, 2001 to 2016. Journal of the American Academy of Dermatology.
  • Fonacier L, Frankel D, Mawhirt S. Contact allergens for the Allergist. Annals of Allergy, Asthma & Immunology.
  • Metz M, et al. The diagnostic workup in chronic spontaneous urticaria—what to test and why. The Journal of Allergy and Clinical Immunology: In Practice.
  • Simpson EL, et al. Patient-oriented measures for phase 3 studies of tralokinumab for the treatment of atopic dermatitis (ECZTRA 1, 2, and 3). Annals of Allergy, Asthma & Immunology.

  Lung

  • Bai Y, Guedes AGP, Krishnan R, Ai X. CD38 plays an age-related role in cholinergic deregulation of airway smooth muscle contractility. Journal of Allergy and Clinical Immunology.
  • Brusselle GG, Koppelman GH. Biologic therapies for severe asthma. New England Journal of Medicine.
  • de Blay F, et al. Which patients with asthma are most likely to benefit from allergen immunotherapy? Journal of Allergy and Clinical Immunology.
  • Douglass JA. Thunderstorm asthma in seasonal allergic rhinitis: The TAISAR study. Journal of Allergy and Clinical Immunology.
  • Kim C, et al. Effectiveness of maintenance and reliever therapy using inhaled corticosteroid–formoterol in asthmatics. The Journal of Allergy and Clinical Immunology: In Practice.

  Food and Drug Allergy/Hypersensitivity Reactions

  • Asero R, et al. Peanut allergy in Italy: A unique Italian perspective. Journal of Allergy and Clinical Immunology: Global.
  • Nowak-Wegrzyn A, Berin MC, Mehr S. Food protein-induced enterocolitis syndrome. The Journal of Allergy and Clinical Immunology: In Practice.
  • Vickery BP, et al. Continuous and daily oral immunotherapy for peanut allergy: Results from a 2-year open-label follow-on study. The Journal of Allergy and Clinical Immunology: In Practice.
  • Zhang J, et al. Evaluation of combination therapy with etanercept and systemic corticosteroids for Stevens-Johnson syndrome and toxic epidermal necrolysis: A multicenter observational study. The Journal of Allergy and Clinical Immunology: In Practice.

  Anaphylaxis

  • Lavery WJ, Stevenson M, Bernstein JA. An overview of seminal plasma hypersensitivity and approach to treatment. The Journal of Allergy and Clinical Immunology: In Practice.
  • Mullins RJ, Dear KBG, Tang MLK. Changes in Australian food anaphylaxis admission rates following introduction of updated allergy prevention guidelines. Journal of Allergy and Clinical Immunology.
  • Patel N, et al. Use of multiple epinephrine doses in anaphylaxis: A systematic review and meta-analysis. Journal of Allergy and Clinical Immunology.
  • Valent P, et al. Global Classification of Mast Cell Activation Disorders: An ICD-10-CM–adjusted proposal of the ECNM-Aim Consortium. The Journal of Allergy and Clinical Immunology: In Practice.

  Immune Hypersensitivity Disorders

  • Bertoni A, et al. Spontaneous NLRP3 inflammasome-driven IL-1-β secretion is induced in severe COVID-19 patients and responds to anakinra treatment. Journal of Allergy and Clinical Immunology.
  • Lin B, Goldbach-Mansky R. Pathogenic insights from genetic causes of autoinflammatory inflammasomopathies and interferonopathies. Journal of Allergy and Clinical Immunology.
  • Papa R, et al. INSAID variant classification and Eurofever Criteria Guide Optimal Treatment Strategy in patients with traps: Data from the Eurofever Registry. The Journal of Allergy and Clinical Immunology: In Practice.

  Immunodeficiencies

  • Blom M, et al. Recommendations for uniform definitions used in newborn screening for severe combined immunodeficiency. Journal of Allergy and Clinical Immunology.
  • Hardin O, Lokhnygina Y, Buckley RH. Long-term clinical outcomes of severe combined immunodeficiency patients given nonablative Marrow Transplants. The Journal of Allergy and Clinical Immunology: In Practice.
  • Lankester AC, et al. Hematopoietic cell transplantation in severe combined immunodeficiency: The SCETIDE 2006-2014 European cohort. Journal of Allergy and Clinical Immunology.
  • Markert ML, Gupton SE, McCarthy EA. Experience with cultured thymus tissue in 105 children. Journal of Allergy and Clinical Immunology.

  Eosinophilic or Gastrointestinal Disorders

  • Dellon ES, et al. Anti–SIGLEC-8 antibody for eosinophilic gastritis and duodenitis. New England Journal of Medicine.
  • Kamat S, et al. Novel questionnaires for assessing signs and symptoms of eosinophilic esophagitis in children. The Journal of Allergy and Clinical Immunology: In Practice.
  • Radonjic-Hoesli S, et al. Characteristics of dermatological patients with blood eosinophilia: A retrospective analysis of 453 patients. The Journal of Allergy and Clinical Immunology: In Practice.
  • Rothenberg ME, et al. Mepolizumab reduces hypereosinophilic syndrome flares irrespective of blood eosinophil count and interleukin-5. The Journal of Allergy and Clinical Immunology: In Practice.

  Emerging National Health Priorities

  • Chiarella SE, et al. Predictors of seroconversion after coronavirus disease 2019 vaccination. Annals of Allergy, Asthma & Immunology.
  • Greiwe J, et al. Boxed warnings and off-label use of allergy medications: Risks, benefits, and shared decision making. The Journal of Allergy and Clinical Immunology: In Practice.
  • Mosnaim GS, et al. Digital inhalers and remote patient monitoring for asthma. The Journal of Allergy and Clinical Immunology: In Practice.
  • Soffer GK, Shroff P, Horwitz R. Safety considerations for natural products commonly used by patients with allergic disease. The Journal of Allergy and Clinical Immunology: In Practice.

• CAP Articles - 2023 Block 1

  Head/Neck

  • Borish L, et al. Yardstick for the medical management of chronic rhinosinusitis. Annals
  • Mullol J, et al. Olfactory outcomes with dupilumab in chronic rhinosinusitis with nasal polyps. JACI in Practice
  • Oykhman P, et al. Comparative efficacy and safety of monoclonal antibodies and aspirin desensitization for chronic rhinosinusitis with nasal polyposis: A systematic review and network meta-analysis. JACI
  • Smith SS, Kim R, Douglas R. Is there a role for antibiotics in the treatment of chronic rhinosinusitis? JACI

  Dermatologic

  • Baeza ML, et al. Angioedema due to acquired deficiency of C1-inhibitor: A cohort study in Spain and a comparison with other series. JACI in Practice
  • Johansen JD, et al. Novel insights into contact dermatitis. JACI
  • Khan DA, et al. What’s new in the treatment of urticaria and angioedema. JACI in Practice
  • Singh AM, et al. Atopic dermatitis and food allergy: Best practices and knowledge gaps—a work group report from the AAAAI Allergic Skin Diseases Committee and Leadership Institute Project. JACI in Practice

  Lung

  • Brennan V, et al. The contribution of oral and inhaled glucocorticoids to adrenal insufficiency in asthma. JACI in Practice
  • Hurrell BP, et al. Cannabinoid receptor 2 engagement promotes group 2 innate lymphoid cell expansion and enhances airway hyperreactivity. JACI
  • Wilson K, et al. The association between duration of breastfeeding and childhood asthma outcomes. Annals

  Food and Drug Allergy/Hypersensitivity Reactions

  • González-Delgado P, et al. Food protein–induced enterocolitis syndrome in adulthood: Clinical characteristics, prognosis, and risk factors. JACI in Practice
  • Li L, et al. Safety, outcomes, and recommendations for two-step outpatient nonsteroidal anti-inflammatory drug challenges. JACI in Practice
  • Peters RL, et al. The natural history of peanut and egg allergy in children up to age 6 years in the HealthNuts population-based longitudinal study. JACI
  • van der Poorten M-LM, et al. Reliability of early and late testing for suspected perioperative hypersensitivity. JACI in Practice

  Anaphylaxis

  • Carra S, et al. Anaphylaxis and pregnancy: A systematic review and call for Public Health Actions. JACI in Practice
  • Cuevas-Bravo C, et al. Kounis syndrome. Annals
  • Gotlib J, et al. Proposed European Competence Network on mastocytosis—american initiative in mast cell diseases (ECNM-AIM) response criteria in advanced systemic mastocytosis. JACI in Practice
  • Meir LR, et al. Anaphylaxis among elderly emergency department patients in a large health system in New York. Annals

  Immune Hypersensitivity Disorders

  • Fijen LM, et al. Inhibition of prekallikrein for hereditary angioedema. NEJM
  • Requena G, et al. Clinical profile and treatment in hypereosinophilic syndrome variants: A pragmatic review. JACI in Practice
  • Schuppan D, et al. A randomized trial of a transglutaminase 2 inhibitor for celiac disease. NEJM

  Immunodeficiencies

  • Barmettler S, et al. Response to severe acute respiratory syndrome coronavirus 2 initial series and additional dose vaccine in patients with predominant antibody deficiency. JACI in Practice
  • Eddens T, et al. Trends in pediatric primary immunodeficiency: Incidence, utilization, transplantation, and mortality. JACI in Practice
  • LaBere B, et al. Chronic granulomatous disease with inflammatory bowel disease: Clinical presentation, treatment, and outcomes from the USIDNET Registry. JACI in Practice
  • Lee TK, Gereige JD, Maglione PJ. State-of-the-art diagnostic evaluation of common variable immunodeficiency. Annals

  Eosinophilic or Gastrointestinal Disorders

  • Chen MM, et al. An international, retrospective study of off-label biologic use in the treatment of hypereosinophilic syndromes. JACI in Practice
  • Dellon ES, Simon D, Wechsler ME. Controversies in allergy: The potential role of biologics as first-line therapy in eosinophilic disorders. JACI in Practice
  • Leiferman KM, Peters MS. Eosinophil-related disease and the skin. JACI in Practice
  • Muir AB, et al. Esophageal remodeling in eosinophilic esophagitis: Relationships to luminal captured biomarkers of inflammation and Periostin. JACI

  Emerging National Health Priorities

  • Biagini JM, et al. Longitudinal atopic dermatitis endotypes: An atopic march paradigm that includes Black Children. JACI
  • Israel E, et al. Reliever-triggered inhaled glucocorticoid in black and Latinx adults with asthma. NEJM
  • Magnus MC, et al. Association of SARS-COV-2 vaccination during pregnancy with pregnancy outcomes. JAMA
  • Sullivan DJ, et al. Early outpatient treatment for covid-19 with convalescent plasma. NEJM

• CAP Articles - 2022 Block 2

  Head and Neck

  • Brown HJ, et al. Defining the Allergic Endotype of Chronic Rhinosinusitis by Structured Histopathology and Clinical Variables. JACI in Practice
  • Delemarre T, et al. A substantial neutrophilic inflammation as regular part of severe type 2 chronic rhinosinusitis with nasal polyps. JACI
  • Rodrigues J, et al. The spectrum of allergic ocular diseases. Annals

  Dermatologic

  • Brar KK. A review of contact dermatitis. Annals
  • Busse PJ, et al. US HAEA Medical Advisory Board 2020 Guidelines for the Management of Hereditary Angioedema. JACI in Practice
  • Maurer M, Khan DA, Elieh Ali Komi D, Kaplan AP. Biologics for the Use in Chronic Spontaneous Urticaria: When and Which. JACI in Practice
  • Nochaiwong S, et al. Impact of pharmacological treatments for chronic spontaneous urticaria with an inadequate response to H1-antihistamines on health-related quality of life: A systematic review and network meta-analysis. JACI in Practice

  Lung

  • Abbas F, Georas S, Cai X, Khurana S. Asthma biologics. Annals
  • Ekström M, et al. Risk of Rehospitalization and Death in Patients Hospitalized Due to Asthma. JACI in Practice
  • Phipatanakul W, et al. Effect of school integrated pest management or classroom air filter purifiers on asthma symptoms in students with active asthma. JAMA
  • Wang Y-H, et al. Association between Proton Pump Inhibitor use and risk of asthma in children. JAMA Pediatrics

  Food and Drug Allergy/Hypersensitivity Reactions

  • Casimir-Brown RS, et al. Piperacillin-tazobactam hypersensitivity: A large, multicenter analysis. JACI in Practice
  • Fleischer DM, et al. A Consensus Approach to the Primary Prevention of Food Allergy Through Nutrition: Guidance from the American Academy of Allergy, Asthma, and Immunology; American College of Allergy, Asthma, and Immunology; and the Canadian Society for Allergy and Clinical Immunology. JACI in Practice
  • Guyer A. Tackling the Patient with Multiple Drug “Allergies”: Multiple Drug Intolerance Syndrome. JACI in Practice
  • Urashima M, et al. Primary prevention of cow’s milk sensitization and food allergy by avoiding supplementation with cow’s milk formula at birth. JAMA Pediatrics

  Anaphylaxis

  • Cianferoni A. Non–IGE-mediated anaphylaxis. JACI
  • Francuzik W, et al. Phenotype and risk factors of venom-induced anaphylaxis: A case-control study of the European Anaphylaxis Registry. JACI
  • Luskin KT, White AA, Lyons JJ. The Genetic Basis and Clinical Impact of Hereditary Alpha-Tryptasemia. JACI in Practice
  • Robinson LB, et al. Trends in US Emergency Department Visits for Anaphylaxis Among Infants and Toddlers: 2006-2015. JACI in Practice

  Immune Hypersensitivity Disorders

  • Egg D, et al. Therapeutic options for ctla-4 insufficiency. JACI
  • Fajgenbaum DC, June CH. Cytokine storm. NEJM
  • Montgomery J. Myocarditis following immunization With Mrna COVID-19 vaccines in members of the US Military. JAMA Cardiology
  • Shields AM, et al. COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experience. JACI

  Immunodeficiencies

  • Abyazi ML, et al. Convergence of cytokine dysregulation and antibody deficiency in common variable immunodeficiency with inflammatory complications. JACI
  • Delmonte OM, et al. Antibody responses to the SARS-COV-2 vaccine in individuals with various inborn errors of immunity. JACI
  • Hale JE, et al. Ten years of newborn screening for severe combined immunodeficiency (SCID) in Massachusetts. JACI in Practice
  • Mauracher AA, et al. Patterns of immune dysregulation in primary immunodeficiencies: A systematic review. JACI in Practice

  Eosinophilic or Gastrointestinal Disorders

  • Bluestein SB, Yu R, Stone CA, Phillips EJ. Reporting of Drug Reaction with Eosinophilia and Systemic Symptoms from 2002-2019 in the FDA Adverse Event Reporting System (FAERS). JACI in Practice
  • DiTommaso LA, et al. Prevalence of eosinophilic colitis and the diagnoses associated with colonic eosinophilia. JACI
  • Szafron V, et al. Assessing health-related quality of life in children with food allergy and eosinophilic esophagitis. JACI in Practice
  • Yamamoto M, et al. Comparison of nonesophageal eosinophilic gastrointestinal disorders with Eosinophilic Esophagitis: A nationwide survey. JACI in Practice

  Emerging National Health Priorities

  • Abrams EM, et al. The COVID-19 pandemic adverse effects on the social determinants of health in children and families. Annals
  • Croce EA, Levy ML, Adamson AS, Matsui EC. Reframing racial and ethnic disparities in atopic dermatitis in black and Latinx populations. JACI
  • Son MB, et al. Multisystem inflammatory syndrome in children — initial therapy and outcomes. NEJM
  • Zhu JM, Polsky D. Private Equity and Physician Medical Practices — Navigating a Changing Ecosystem. NEJM

• CAP Articles - 2022 Block 1

  Head and Neck

  • Addison AB, et al. Clinical Olfactory Working Group consensus statement on the treatment of postinfectious olfactory dysfunction. JACI
  • Bachert C, et al. Biologics for chronic rhinosinusitis with nasal polyps. JACI
  • Kwah JH, et al. Clinical factors associated with acute exacerbations of chronic rhinosinusitis. JACI
  • Nolte H, et al. Efficacy and Safety of Ragweed SLIT-Tablet in Children with Allergic Rhinoconjunctivitis in a Randomized, Placebo-Controlled Trial. JACI in Practice

  Dermatologic

  • Bieber T, et al. Abrocitinib versus Placebo or Dupilumab for Atopic Dermatitis. NEJM
  • Guttman-Yassky E, et al. Upadacitinib in adults with moderate to severe atopic dermatitis: 16-week results from a randomized, placebo-controlled trial. JACI
  • Ratchataswan T, et al. Biologics for Treatment of Atopic Dermatitis: Current Status and Future Prospect. JACI in Practice
  • Tsoi LC, et al. Progression of acute-to-chronic atopic dermatitis is associated with quantitative rather than qualitative changes in cytokine responses. JACI

  Lung

  • Abdulqawi R, et al. A Randomized Controlled Trial to Assess the Effect of Lidocaine Administered via Throat Spray and Nebulization in Patients with Refractory Chronic Cough. JACI in Practice
  • Cazzola M, Rogliani P, Matera MG. The latest on the role of LAMAs in asthma. JACI
  • Pavord ID, et al. Clinical Development of Mepolizumab for the Treatment of Severe Eosinophilic Asthma: On the Path to Personalized Medicine. JACI in Practice

  Food and Drug Allergy/Hypersensitivity Reactions

  • Cox AL, Eigenmann PA, Sicherer SH. Clinical Relevance of Cross-Reactivity in Food Allergy. JACI in Practice
  • Greenhawt M. Peanut allergy diagnosis: A 2020 practice parameter update, systematic review, and GRADE analysis. JACI
  • Mori F, et al. A Multicenter Retrospective Study on Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) in Children: A Report from the European Network on Drug Allergy (ENDA) Group. JACI in Practice
  • Waserman S, et al. Prevention and management of allergic reactions to food in child care centers and schools: Practice guidelines. JACI

  Anaphylaxis

  • Carter MC, et al. Idiopathic anaphylaxis yardstick: Practical recommendations for clinical practice. Annals
  • González-de-Olano, D, Matito A, lvarez-Twose I. Mast cell activation syndromes and anaphylaxis: Multiple diseases part of the same spectrum. Annals
  • Lieberman JA, Bingemann TA, Wang J. Diagnostic Challenges in Anaphylaxis. JACI in Practice
  • Schuler CF, et al. Prevalence of mastocytosis and hymenoptera venom allergy in the United States. JACI

  Immune Hypersensitivity Disorders

  • Greinacher A, et al. Thrombotic thrombocytopenia after Chadox1 Ncov-19 vaccination. NEJM
  • Johnson DB, Jakubovic BD, Sibaud V, Sise ME. Balancing Cancer Immunotherapy Efficacy and Toxicity. JACI in Practice
  • Nigrovic PA, Lee PY, Hoffman HM. Monogenic autoinflammatory disorders: Conceptual overview, phenotype, and clinical approach. JACI

  Immunodeficiencies

  • Cepika A-M, et al. Tregopathies: Monogenic diseases resulting in regulatory T-cell deficiency. JACI
  • Peter H-H, et al. Targeting FcRn for immunomodulation: Benefits, risks, and practical considerations. JACI
  • Thalhammer J, et al. Initial presenting manifestations in 16,486 patients with inborn errors of immunity Include infections And Noninfectious manifestations. JACI
  • Verbsky JW, et al. Rituximab and antimetabolite treatment of granulomatous and lymphocytic interstitial lung disease in common variable immunodeficiency. JACI

  Eosinophilic or Gastrointestinal Disorders

  • Carpentier C, et al. CD3−CD4+ Lymphocytic Variant Hypereosinophilic Syndrome: Diagnostic Tools Revisited. JACI in Practice
  • Lefèvre G, et al. “Idiopathic Eosinophilic Vasculitis”: Another Side of Hypereosinophilic Syndrome? A Comprehensive Analysis of 117 Cases in Asthma-Free Patients. JACI in Practice
  • Lyles JL, et al. Very early onset eosinophilic esophagitis is common, responds to standard therapy, and demonstrates enrichment for CAPN14 genetic variants. JACI
  • Roufosse F, et al. Efficacy and safety of mepolizumab in hypereosinophilic syndrome: A phase III, randomized, placebo-controlled trial. JACI

  Emerging National Health Priorities

  • Bingemann TA, Laubach S. Physician well-being in allergy and immunology. Annals
  • Gudbjartsson DF, et al. Humoral Immune Response to SARS-CoV-2 in Iceland. NEJM
  • Krist AH, et al. Screening for Vitamin D Deficiency in Adults US Preventive Services Task Force Recommendation Statement. JAMA
  • Ogbogu PU, Capers Q, Apter AJ. Disparities in Asthma and Allergy Care: What Can We Do? JACI in Practice
  • Risma KA, et al. Potential mechanisms of anaphylaxis to COVID-19 mRNA vaccines. JACI

• CAP Articles - 2021 Block 2

  Head and Neck

  • Delemarre T, et al. Type 2 inflammation in chronic rhinosinusitis without nasal polyps: Another relevant endotype. JACI
  • Dykewicz M, et al. Rhinitis 2020: A practice parameter update. JACI
  • Gevaert P, et al. Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials. JACI

  Dermatologic

  • Kabashima K, Matsumura T, Komazaki H, Kawashima M. Trial of Nemolizumab and Topical Agents for Atopic Dermatitis with Pruritus. NEJM
  • Ravn NH, et al. How does parental history of atopic disease predict the risk of atopic dermatitis in a child? A systematic review and meta-analysis. JACI
  • Rehbinder EM. Predicting Skin Barrier Dysfunction and Atopic Dermatitis in Early Infancy. JACI in Practice
  • Wang V, Boguniewicz J, Boguniewicz M, Ong PY. The infectious complications of atopic dermatitis. Annals

  Lung

  • Guntur VP, et al. Benralizumab as a Steroid-Sparing Treatment Option in Eosinophilic Granulomatosis with Polyangiitis. JACI in Practice
  • Miethe S, Karsonova A, Karaulov A, Renz H. Obesity and asthma. JACI
  • Skevaki C, et al. Asthma-associated risk for COVID-19 development. JACI
  • Stevens WW, et al. The role of aspirin desensitization followed by oral aspirin therapy in managing patients with aspirin-exacerbated respiratory disease: A Work Group Report from the Rhinitis, Rhinosinusitis and Ocular Allergy Committee of the American Academy of Allergy, Asthma & Immunology. JACI

  Food and Drug Allergy/Hypersensitivity Reactions

  • Broyles AD, et al. Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs. JACI in Practice
  • Castells M, Khan DA, Phillips EJ. Penicillin Allergy. NEJM
  • Kim EH, et al. Induction of sustained unresponsiveness after egg oral immunotherapy compared to baked egg therapy in children with egg allergy. JACI
  • Suprun M, et al. Early epitope-specific IgE antibodies are predictive of childhood peanut allergy. JACI

  Anaphylaxis

  • Chapsa M, et al. Predictors of severe anaphylaxis in Hymenoptera venom allergy: The importance of absence of urticaria and angioedema. Annals
  • Greenhawt M, et al. Guiding Principles for the Recognition, Diagnosis, and Management of Infants with Anaphylaxis: An Expert Panel Consensus. JACI in Practice
  • Hartmann K, et al. Midostaurin improves quality of life and mediator-related symptoms in advanced systemic mastocytosis. JACI
  • Turner PJ, Campbell DE, Motosue MS, Campbell RL. Global Trends in Anaphylaxis Epidemiology and Clinical Implications. JACI in Practice

  Immune Hypersensitivity Disorders

  • Asano K, et al. New clinical diagnostic criteria for allergic bronchopulmonary aspergillosis/mycosis and its validation. JACI
  • Farmer JR, Uzel G. Mapping Out Autoimmunity Control in Primary Immune Regulatory Disorders. JACI in Practice
  • Gustafson CE, Kim C, Weyand CM, Goronzy JJ. Influence of immune aging on vaccine responses. JACI
  • Habibi S, et al. Clinical, Immunologic, and Molecular Spectrum of Patients with LPS-Responsive Beige-Like Anchor Protein Deficiency: A Systematic Review. JACI in Practice

  Immunodeficiencies

  • Deya-Martinez A, Flinn AM, Gennery AR. Neonatal thymectomy in children—accelerating the immunologic clock? JACI
  • Lorenzini T, et al. Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations. JACI
  • Lu HY, et al. Germline CBM-opathies: From immunodeficiency to atopy. JACI
  • Meyts I, et al. Coronavirus disease 2019 in patients with inborn errors of immunity: An international study. JACI

  Eosinophilic or Gastrointestinal Disorders

  • Goldberg MR, et al. Risk Factors and Treatment Outcomes for Oral Immunotherapy–Induced Gastrointestinal Symptoms and Eosinophilic Responses (OITIGER). JACI in Practice
  • Gonsalves NP, Aceves SS. Diagnosis and treatment of eosinophilic esophagitis. JACI
  • Kuang FL, et al. Single-Organ and Multisystem Hypereosinophilic Syndrome Patients with Gastrointestinal Manifestations Share Common Characteristics. JACI in Practice

  Emerging National Health Priorities

  • Dyrbye LN, et al. Effect of a Professional Coaching Intervention on the Well-being and Distress of Physicians A Pilot Randomized Clinical Trial. JAMA Internal Medicine
  • Ganguli I, et al. Physician Work Hours and the Gender Pay Gap — Evidence from Primary Care. NEJM
  • Gu T, et al. Characteristics Associated With Racial/Ethnic Disparities in COVID-19 Outcomes in an Academic Health Care System. JAMA Network Open
  • Lovinsky-Desir S, et al. Asthma among hospitalized patients with COVID-19 and related outcomes. JACI
  • McKenzie C, Silverberg JI. The prevalence and persistence of atopic dermatitis in urban United States children. Annals

• CAP Articles - 2021 Block 1

  Head and Neck

  • Bédard A, et al. Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study. JACI
  • Bielory L, et al. ICON Diagnosis and management of allergic conjunctivitis. Annals
  • Stevens WW, et al. Associations Between Inflammatory Endotypes and Clinical Presentations in Chronic Rhinosinusitis. JACI in Practice

  Dermatologic

  • Fishbein AB, et al. Update on Atopic Dermatitis: Diagnosis, Severity Assessment, and Treatment Selection. JACI in Practice
  • Johal KJ, Saini SS. Current and emerging treatments for chronic spontaneous urticaria. Annals
  • Miyaji Y, et al. Earlier aggressive treatment to shorten the duration of eczema in infants resulted in fewer food allergies at 2 years of age. JACI in Practice

  Lung

  • Barnes PJ, et al. Symptoms and perception of airway obstruction in asthmatic patients: Clinical implications for use of reliever medications. JACI
  • Cohen JM, et al. Poorly Controlled Asthma During Pregnancy Remains Common in the United States. JACI in Practice
  • Generoso A, Tuong L, Oppenheimer J. Treatment strategies for the yellow zone. Annals
  • Mikhail I, Grayson MH. Asthma and viral infections An intricate relationship. Annals

  Food and Drug Allergy/Hypersensitivity Reactions

  • Konvinse KK, et al. HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms. JACI
  • Park HJ, et al. Unique Clinical Characteristics and Prognosis of Allopurinol-Induced Severe Cutaneous Adverse Reactions. JACI in Practice
  • Perkin MR, et al. Efficacy of the Enquiring About Tolerance (EAT) study among infants at high risk of developing food allergy. JACI

  Anaphylaxis

  • Platts-Mills TAE, et al. Diagnosis and Management of Patients with the a-Gal Syndrome. JACI in Practice
  • Ramsey NB, et al. Epidemiology of Anaphylaxis in Critically Ill Children in the United States and Canada. JACI in Practice
  • Weiler CR, et al. AAAAI Mast Cell Disorders Committee Work Group Report: Mast cell activation syndrome (MCAS) diagnosis and management. JACI

  Immune Hypersensitivity Disorders

  • Agarwal S, Cunningham-Rundles C. Autoimmunity in common variable immunodeficiency. Annals
  • Fabre A, et al. Clinical Aspects of STAT3 Gain-of-Function Germline Mutations: A Systematic Review. JACI in Practice
  • Sha BE. Adult Immunization Update. JAMA

  Immunodeficiencies

  • Gupta S, et al. Tolerability of Ig20Gly during onboarding in patients with primary immunodeficiency diseases. Annals
  • Romberg N, Lawrence MG. Birds of a feather Common variable immune deficiencies. Annals
  • Seidel M, et al. The European Society for Immunodeficiencies (ESID) Registry Working Definitions for the Clinical Diagnosis of Inborn Errors of Immunity. JACI in Practice

  Eosinophilic or Gastrointestinal Disorders

  • Groetch M, et al. Dietary Therapy and Nutrition Management of Eosinophilic Esophagitis: A Work Group Report of the American Academy of Allergy, Asthma, and Immunology. JACI in Practice
  • Steinbach EC, Hernandez M, Dellon ES. Eosinophilic Esophagitis and the Eosinophilic Gastrointestinal Diseases: Approach to Diagnosis and Management. JACI in Practice
  • Wu EY, et al. Eosinophilic Granulomatosis with Polyangiitis: Clinical Pathology Conference and Review. JACI in Practice

• CAP Articles - 2020 Block 1

  Head and Neck

  • Jerschow E, et al. Sinus Surgery Is Associated with a Decrease in Aspirin-Induced Reaction Severity in Patients with Aspirin Exacerbated Respiratory Disease. JACI in Practice
  • Leopold DA, et al. NAVIGATE II: Randomized, double-blind trial of the exhalation delivery system with fluticasone for nasal polyposis. JACI
  • Singh U, Wangia-Anderson V, Bernstein J. Chronic Rhinitis Is a High-Risk Comorbidity for 30-Day Hospital Readmission of Patients with Asthma and Chronic Obstructive Pulmonary Disease. JACI in Practice

  Dermatologic

  • Brar K, Nicol N, Boguniewicz M. Strategies for Successful Management of Severe Atopic Dermatitis. JACI in Practice
  • Craig T, et al. Long-Term Outcomes with Subcutaneous C1-Inhibitor Replacement Therapy for Prevention of Hereditary Angioedema Attacks. JACI in Practice
  • Milam EC, Jacob SE, Cohen DE. Contact Dermatitis in the Patient with Atopic Dermatitis. JACI in Practice

  Lung

  • Beasley R, et al. Controlled Trial of Budesonide–Formoterol as Needed for Mild Asthma. NEJM
  • Khatri S, et al. Assessment of the long-term safety of mepolizumab and durability of clinical response in patients with severe eosinophilic asthma. JACI
  • Simmons R, et al. Case 16-2019: A 53-Year-Old Man with Cough and Eosinophilia. NEJM

  Food and Drug Allergy/Hypersensitivity Reactions

  • Dunlop J, et al. Long-Term Follow-Up After Baked Milk Introduction. JACI in Practice
  • Shenoy E, et al. Evaluation and Management of Penicillin Allergy A Review. JAMA
  • Venter C, Sicherer S, Greenhawt M. Management of Peanut Allergy. JACI in Practice

  Anaphylaxis

  • Golden D, Carter G. Insect Sting Anaphylaxis—Or Mastocytosis—Or Something Else? JACI in Practice
  • Kennard L. A Multicenter Evaluation of Diagnosis and Management of Omega-5 Gliadin Allergy (Also Known as Wheat-Dependent Exercise-Induced Anaphylaxis) in 132 Adults. JACI in Practice
  • Shrestha P, et al. Trends in hospitalizations related to anaphylaxis, angioedema, and urticaria in the United States. Annals
  • Su J, et al. Anaphylaxis after vaccination reported to the Vaccine Adverse Event Reporting System, 1990-2016. JACI

  Immune Hypersensitivity Disorders

  • Davis M, van der Hilst J. Mimickers of Urticaria: Urticarial Vasculitis and Autoinflammatory Diseases. JACI in Practice
  • June C, Sadelain M. Chimeric Antigen Receptor Therapy. NEJM
  • Montalban X, et al. Placebo-Controlled Trial of an Oral BTK Inhibitor in Multiple Sclerosis. NEJM

  Immunodeficiencies

  • Filion C, et al. Differentiation of Common Variable Immunodeficiency From IgG Deficiency. JACI in Practice
  • Harris KM, et al. Virus-Specific T Cells: Current and Future Use in Primary Immunodeficiency Disorders. JACI in Practice
  • Scott O, Roifman C. NF-kB pathway and the Goldilocks principle: Lessons from human disorders of immunity and inflammation. JACI

  Eosinophilic or Gastrointestinal Disorders

  • Burris D, et al. Pediatric Hypereosinophilia: Characteristics, Clinical Manifestations, and Diagnoses. JACI in Practice
  • Khoury P, Bochner B. Consultation for Elevated Blood Eosinophils: Clinical Presentations, High Value Diagnostic Tests, and Treatment Options. JACI in Practice
  • Kuang FL, et al. Benralizumab for PDGFRA-Negative Hypereosinophilic Syndrome. NEJM

• CAP Articles - 2019 Block 2

  Head and Neck

  • Weinstein S, et al. Efficacy and safety of dupilumab in perennial allergic rhinitis and comorbid asthma. JACI
  • Niederberger V, et al. Safety and efficacy of immunotherapy with the recombinant B-cell epitope–based grass pollen vaccine BM32. JACI
  • Ta LDH, et al. Establishment of the nasal microbiota in the first 18 months of life: Correlation with early-onset rhinitis and wheezing. JACI

  Dermatologic

  • Maurer M, Fluhr J, Khan D. How to Approach Chronic Inducible Urticaria. JACI in Practice
  • AygörenPürsün E, et al. Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema. NEJM
  • Fonacier L, Noor I. Contact dermatitis and patch testing for the allergist. Annals

  Lung

  • Dekhuijzen R, et al. Addressing the Impact and Unmet Needs of Nonadherence in Asthma and Chronic Obstructive Pulmonary Disease: Where Do We Go From Here? JACI in Practice
  • Chipps B, et al. The pediatric asthma yardstick Practical recommendations for a sustained step-up in asthma therapy for children with inadequately controlled asthma. Annals
  • Jackson DJ, et al. Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations. NEJM

  Food and Drug Allergy/Hypersensitivity Reactions

  • Kuyucu S, Caubet J-C. Hypersensitivity Reactions to Antiepileptic Drugs in Children: Epidemiologic, Pathogenetic, Clinical, and Diagnostic Aspects. JACI in Practice
  • Macy E, Vyles D. Who needs penicillin allergy testing? Annals
  • Schuyler A, et al. Specific IgG4 antibodies to cow’s milk proteins in pediatric patients with eosinophilic esophagitis. JACI

  Anaphylaxis

  • Carter M, et al. A distinct biomolecular profile identifies monoclonal mast cell disorders in patients with idiopathic anaphylaxis. JACI
  • Wright C, et al. An analysis of anaphylaxis cases at a single pediatric emergency department during a 1-year period. Annals
  • Bonadonna P, et al. Anaphylactic Reactions After Discontinuation of Hymenoptera Venom Immunotherapy: A Clonal Mast Cell Disorder Should Be Suspected. JACI in Practice
  • Motosue M, et al. Outcomes of Emergency Department Anaphylaxis Visits from 2005 to 2014. JACI in Practice

  Hypersensitivity Disorders

  • De Benedetti F, et al. Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes. NEJM
  • Wechsler ME, et al. Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis. NEJM
  • Isabwe G, et al. Hypersensitivity reactions to therapeutic monoclonal antibodies: Phenotypes and endotypes. JACI

  Immunodeficiencies

  • Hajjar J, et al. Questioning the accuracy of currently available pneumococcal antibody testing. JACI
  • Mayor P, et al. Cancer in primary immunodeficiency diseases: Cancer incidence in the United States Immune Deficiency Network Registry. JACI
  • Bonilla F. Update: Vaccines in primary immunodeficiency. Journal of Allergy and Clinical Immunology. JACI

  Eosinophilic and Gastrointestinal Disorders

  • Khoury P, et al. Hypereosinophilic Syndrome Subtype Predicts Responsiveness to Glucocorticoids. JACI in Practice
  • Barbosa A, et al. Eosinophilic Esophagitis: Latent Disease in Patients with Anaphylactic Reaction to Cow’s Milk. JACI in Practice
  • Wechsler J, Hirano I. Biological therapies for eosinophilic gastrointestinal diseases. JACI

• CAP Articles - 2019 Block 1

  Head and Neck

  • Ellis A, et al. Lack of effect of Timothy grass pollen sublingual immunotherapy tablet on birch pollen–induced allergic rhinoconjunctivitis in an environmental exposure unit. Annals
  • Bachert C, et al. Reduced need for surgery in severe nasal polyposis with mepolizumab: Randomized trial. JACI
  • Chang E, et al. Early life risk factors for chronic sinusitis: A longitudinal birth cohort study. JACI

  Dermatologic

  • Hamad A, Jithpratuck W, Krishnaswamy G. Urticarial vasculitis and associated disorders. Annals
  • Czarnowicki T, et al. Novel concepts of prevention and treatment of atopic dermatitis through barrier and immune manipulations with implications for the atopic march. JACI
  • Yosipovitch G, et al. Serlopitant for the treatment of chronic pruritus: Results of a randomized, multicenter, placebo-controlled phase 2 clinical trial. JAAD

  Lung

  • Dicker A, et al. Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease. JACI
  • Mukherjee M, et al. Sputum autoantibodies in patients with severe eosinophilic asthma. JACI
  • Desai M, Oppenheimer J, Tashkin D. Asthma-chronic obstructive pulmonary disease overlap syndrome What we know and what we need to find out. Annals

  Food and Drug Allergy/Hypersensitivity Reactions

  • Santos A, Brough H. Making the Most of In Vitro Tests to Diagnose Food Allergy. JACI in Practice
  • Sampson H, et al. Effect of Varying Doses of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Exposure Among Patients With Peanut Sensitivity. JAMA
  • Ierodiakonou D, et al. Timing of Allergenic Food Introduction to the Infant Diet and Risk of Allergic or Autoimmune Disease. JAMA

  Anaphylaxis

  • Lieberman P, et al. Anaphylaxis associated with omalizumab administration: Risk factors and patient characteristics. JACI
  • Lee S, et al. Trends, characteristics, and incidence of anaphylaxis in 2001-2010: A population-based study. JACI
  • Buka R, et al. Anaphylaxis and Clinical Utility of Real-World Measurement of Acute Serum Tryptase in UK Emergency Departments. JACI

  Hypersensitivity Disorders

  • Steri M, et al. Overexpression of the Cytokine BAFF and Autoimmunity Risk. NEJM
  • Cunningham A.L., et al. Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older. NEJM
  • Johnson D, et al. Fulminant Myocarditis with Combination Immune Checkpoint Blockade. NEJM

  Immunodeficiencies

  • Banerji A, et al. Inhibiting Plasma Kallikrein for Hereditary Angioedema Prophylaxis. NEJM
  • Monach P, et al. Case 6-2017: A 57-Year-Old Woman with Fatigue, Sweats, Weight Loss, Headache, and Skin Lesions. NEJM
  • De la Morena MT, et al. Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation. JACI

  Eosinophilic and Gastrointestinal Disorders

  • O'Sullivan J, Bochner B. Eosinophils and eosinophil-associated diseases: An update. JACI
  • Spergel J, Aceves S. Allergic components of eosinophilic esophagitis. JACI
  • Kuang F, Klion A. Biologic Agents for the Treatment of Hypereosinophilic Syndromes. JACI in Practice

• CAP Articles - 2018 Block 2

  Head and Neck

  • Campbell AP, et al. Depression symptoms and lost productivity in chronic rhinosinusitis. Annals
  • Hui JW, et al. Risk of obstructive sleep apnea in African American patients with chronic rhinosinusitis. Annals
  • Stevens WW, et al. Clinical Characteristics of Patients with Chronic Rhinosinusitis with Nasal Polyps, Asthma, and Aspirin-Exacerbated Respiratory Disease. JACI in Practice

  Dermatologic

  • Druey KM, Parikh SM. Idiopathic systemic capillary leak syndrome (Clarkson disease). JACI
  • Fonacier L. A Practical Guide to Patch Testing. JACI in Practice
  • Paller AS, Kabashima K, Bieber T. Therapeutic pipeline for atopic dermatitis: End of the drought? JACI

  Lung

  • Corren J, et al. Tezepelumab in Adults with Uncontrolled Asthma. NEJM
  • Guilbert TW, et al. Real-Life Outcomes for Patients with Asthma Prescribed Spacers for Use with Either Extrafine- or Fine-Particle Inhaled Corticosteroids. JACI in Practice
  • Nair P, et al. Oral Glucocorticoid–Sparing Effect of Benralizumab in Severe Asthma. NEJM

  Food and Drug Allergy/Hypersensitivity Reactions

  • Coop CA, Schapira RS, Freeman TM. Are ACE Inhibitors and Beta-blockers Dangerous in Patients at Risk for Anaphylaxis? JACI in Practice
  • Jones SM, Burks AW. Food Allergy. NEJM
  • Vickery BP, et al. Early oral immunotherapy in peanut-allergic preschool children is safe and highly effective. JACI

  Anaphylaxis

  • Castells, M. Diagnosis and management of anaphylaxis in precision medicine. JACI
  • Feldweg AM. Food-Dependent, Exercise-Induced Anaphylaxis: Diagnosis and Management in the Outpatient Setting. JACI in Practice
  • Motosue MS, et al. Risk factors for severe anaphylaxis in the United States. Annals

  Hypersensitivity Disorders

  • Allenspach E, Torgerson TR. Autoimmunity and Primary Immunodeficiency Disorders. J Clin Immunol
  • Andersen YMF, et al. Autoimmune diseases in adults with atopic dermatitis. JAAD
  • Kanneganti T-D. Inflammatory Bowel Disease and the NLRP3 Inflammasome. NEJM

  Immunodeficiencies

  • Sullivan KE, et al. Emerging Infections and Pertinent Infections Related to Travel for Patients with Primary Immunodeficiencies. J Clin Immunol
  • Walter JE, et al. Mechanism-Based Strategies for the Management of Autoimmunity and Immune Dysregulation in Primary Immunodeficiencies. JACI in Practice
  • Wirsum C, et al. Secondary Antibody Deficiency in Glucocorticoid Therapy Clearly Differs from Primary Antibody Deficiency. J Clin Immunol

  Eosinophilic and Gastrointestinal Disorders

  • Chen Y-YK, et al. Marked and persistent eosinophilia in the absence of clinical manifestations. JACI
  • Molina-Infante J, et al. Step-up empiric elimination diet for pediatric and adult eosinophilic esophagitis: The 2-4-6 study. JACI
  • Pannaraj PS, et al. Association Between Breast Milk Bacterial Communities and Establishment and Development of the Infant Gut Microbiome. JAMA Pediatrics

• CAP Articles - 2018 Block 1

  Head and Neck

  • Li JT, et al. Sublingual grass and ragweed immunotherapy: Clinical considerations-a PRACTALL consensus report. JACI
  • Bachert, C. Effect of subcutaneous dupilumab on nasal polyp burden in patients with chronic sinusitis and nasal polyposis. JAMA
  • Berard A, et al. Intranasal triamcinolone use during pregnancy and the risk of adverse pregnancy outcomes. JACI

  Dermatologic

  • Nomura, T. Advances in Atopic Dermatitis. JACI
  • Fonacier L, et al. Contact Dermatitis: A Practice Parameter-Update 2015. JACI in Practice
  • Simpson EL, et al. Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis. NEJM

  Lung

  • Virchow, et al. Efficacy of House Dust Mite Sublingual Allergen Immunotherapy Tablet in Adults with Allergic Rhinitis. JAMA
  • Berry, A. Biomarkers in asthmatic patients: Has their time come to direct treatment? JACI
  • Bowatte, G. Traffic-related air pollution exposure is associated with allergic sensitization, asthma, and poor lung function in middle age. JACI

  Food and Drug Allergy/Hypersensitivity Reactions

  • Wood, RA. Food allergen immunotherapy: Current status and prospects for the future. JACI
  • Perkin MR, et al. Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants. NEJM
  • Togias, Alkis. Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases sponsored expert panel. Annals

  Anaphylaxis

  • Golden, et al. Stinging insect hypersensitivity: A practice parameter update 2016. Annals
  • Lieberman, P., et al. Anaphylaxis – a practice parameter update 2015. Annals
  • De Schryver, S, et al. Tryptase levels in children presenting with anaphylaxis: Temporal trends and associated factors. JACI

  Hypersensitivity Disorders

  • Her, M. Alterations in immune function with biologic therapies for autoimmune disease. JACI
  • Green, PHR. Celiac Disease. JACI
  • Hoffman, HM. The role of the inflammasome in patients with autoinflammatory diseases. JACI

  Immunodeficiencies

  • Gudmundsdottir, Judith. Early thymectomy leads to premature immunologic ageing: An 18-year follow-up. JACI
  • Loffredo L, et al. Chronic granulomatous disease as an SOS call for multicenter cooperative effort to prevent infections. Annals
  • Bonilla, FA. Practice parameter for the diagnosis and management of primary immunodeficiency. JACI

  Eosinophilic and Gastrointestinal Disorders

  • Williams KW, et al. Hypereosinophilia in Children and Adults: a retrospective comparison. JACI in Practice
  • Blumenthal KG, et al. Peripheral blood eosinophilia and hypersensitivity reactions among patients receiving outpatient parenteral antibiotics. JACI
  • Furuta, GT. Eosinophilic Esophagitis. NEJM