News and Publications

CAP Articles - 2021 Block 1

Head and Neck

  • Bédard A, et al. Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study. JACI
  • Bielory L, et al. ICON Diagnosis and management of allergic conjunctivitis. Annals
  • Stevens WW, et al. Associations Between Inflammatory Endotypes and Clinical Presentations in Chronic Rhinosinusitis. JACI in Practice

Dermatologic

  • Fishbein AB, et al. Update on Atopic Dermatitis: Diagnosis, Severity Assessment, and Treatment Selection. JACI in Practice
  • Johal KJ, Saini SS. Current and emerging treatments for chronic spontaneous urticaria. Annals
  • Miyaji Y, et al. Earlier aggressive treatment to shorten the duration of eczema in infants resulted in fewer food allergies at 2 years of age. JACI in Practice

Lung

  • Barnes PJ, et al. Symptoms and perception of airway obstruction in asthmatic patients: Clinical implications for use of reliever medications. JACI
  • Cohen JM, et al. Poorly Controlled Asthma During Pregnancy Remains Common in the United States. JACI in Practice
  • Generoso A, Tuong L, Oppenheimer J. Treatment strategies for the yellow zone. Annals
  • Mikhail I, Grayson MH. Asthma and viral infections An intricate relationship. Annals

Food and Drug Allergy/Hypersensitivity Reactions

  • Konvinse KK, et al. HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms. JACI
  • Park HJ, et al. Unique Clinical Characteristics and Prognosis of Allopurinol-Induced Severe Cutaneous Adverse Reactions. JACI in Practice
  • Perkin MR, et al. Efficacy of the Enquiring About Tolerance (EAT) study among infants at high risk of developing food allergy. JACI

Anaphylaxis

  • Platts-Mills TAE, et al. Diagnosis and Management of Patients with the a-Gal Syndrome. JACI in Practice
  • Ramsey NB, et al. Epidemiology of Anaphylaxis in Critically Ill Children in the United States and Canada. JACI in Practice
  • Weiler CR, et al. AAAAI Mast Cell Disorders Committee Work Group Report: Mast cell activation syndrome (MCAS) diagnosis and management. JACI

Immune Hypersensitivity Disorders

  • Agarwal S, Cunningham-Rundles C. Autoimmunity in common variable immunodeficiency. Annals
  • Fabre A, et al. Clinical Aspects of STAT3 Gain-of-Function Germline Mutations: A Systematic Review. JACI in Practice
  • Sha BE. Adult Immunization Update. JAMA

Immunodeficiencies

  • Gupta S, et al. Tolerability of Ig20Gly during onboarding in patients with primary immunodeficiency diseases. Annals
  • Romberg N, Lawrence MG. Birds of a feather Common variable immune deficiencies. Annals
  • Seidel M, et al. The European Society for Immunodeficiencies (ESID) Registry Working Definitions for the Clinical Diagnosis of Inborn Errors of Immunity. JACI in Practice

Eosinophilic or Gastrointestinal Disorders

  • Groetch M, et al. Dietary Therapy and Nutrition Management of Eosinophilic Esophagitis: A Work Group Report of the American Academy of Allergy, Asthma, and Immunology. JACI in Practice
  • Steinbach EC, Hernandez M, Dellon ES. Eosinophilic Esophagitis and the Eosinophilic Gastrointestinal Diseases: Approach to Diagnosis and Management. JACI in Practice
  • Wu EY, et al. Eosinophilic Granulomatosis with Polyangiitis: Clinical Pathology Conference and Review. JACI in Practice


Prior Blocks

  • CAP Articles - 2020 Block 1

    Head and Neck

    • Jerschow E, et al. Sinus Surgery Is Associated with a Decrease in Aspirin-Induced Reaction Severity in Patients with Aspirin Exacerbated Respiratory Disease. JACI in Practice
    • Leopold DA, et al. NAVIGATE II: Randomized, double-blind trial of the exhalation delivery system with fluticasone for nasal polyposis. JACI
    • Singh U, Wangia-Anderson V, Bernstein J. Chronic Rhinitis Is a High-Risk Comorbidity for 30-Day Hospital Readmission of Patients with Asthma and Chronic Obstructive Pulmonary Disease. JACI in Practice

    Dermatologic

    • Brar K, Nicol N, Boguniewicz M. Strategies for Successful Management of Severe Atopic Dermatitis. JACI in Practice
    • Craig T, et al. Long-Term Outcomes with Subcutaneous C1-Inhibitor Replacement Therapy for Prevention of Hereditary Angioedema Attacks. JACI in Practice
    • Milam EC, Jacob SE, Cohen DE. Contact Dermatitis in the Patient with Atopic Dermatitis. JACI in Practice

    Lung

    • Beasley R, et al. Controlled Trial of Budesonide–Formoterol as Needed for Mild Asthma. NEJM
    • Khatri S, et al. Assessment of the long-term safety of mepolizumab and durability of clinical response in patients with severe eosinophilic asthma. JACI
    • Simmons R, et al. Case 16-2019: A 53-Year-Old Man with Cough and Eosinophilia. NEJM

    Food and Drug Allergy/Hypersensitivity Reactions

    • Dunlop J, et al. Long-Term Follow-Up After Baked Milk Introduction. JACI in Practice
    • Shenoy E, et al. Evaluation and Management of Penicillin Allergy A Review. JAMA
    • Venter C, Sicherer S, Greenhawt M. Management of Peanut Allergy. JACI in Practice

    Anaphylaxis

    • Golden D, Carter G. Insect Sting Anaphylaxis—Or Mastocytosis—Or Something Else? JACI in Practice
    • Kennard L. A Multicenter Evaluation of Diagnosis and Management of Omega-5 Gliadin Allergy (Also Known as Wheat-Dependent Exercise-Induced Anaphylaxis) in 132 Adults. JACI in Practice
    • Shrestha P, et al. Trends in hospitalizations related to anaphylaxis, angioedema, and urticaria in the United States. Annals
    • Su J, et al. Anaphylaxis after vaccination reported to the Vaccine Adverse Event Reporting System, 1990-2016. JACI

    Immune Hypersensitivity Disorders

    • Davis M, van der Hilst J. Mimickers of Urticaria: Urticarial Vasculitis and Autoinflammatory Diseases. JACI in Practice
    • June C, Sadelain M. Chimeric Antigen Receptor Therapy. NEJM
    • Montalban X, et al. Placebo-Controlled Trial of an Oral BTK Inhibitor in Multiple Sclerosis. NEJM

    Immunodeficiencies

    • Filion C, et al. Differentiation of Common Variable Immunodeficiency From IgG Deficiency. JACI in Practice
    • Harris KM, et al. Virus-Specific T Cells: Current and Future Use in Primary Immunodeficiency Disorders. JACI in Practice
    • Scott O, Roifman C. NF-kB pathway and the Goldilocks principle: Lessons from human disorders of immunity and inflammation. JACI

    Eosinophilic or Gastrointestinal Disorders

    • Burris D, et al. Pediatric Hypereosinophilia: Characteristics, Clinical Manifestations, and Diagnoses. JACI in Practice
    • Khoury P, Bochner B. Consultation for Elevated Blood Eosinophils: Clinical Presentations, High Value Diagnostic Tests, and Treatment Options. JACI in Practice
    • Kuang FL, et al. Benralizumab for PDGFRA-Negative Hypereosinophilic Syndrome. NEJM
  • CAP Articles - 2019 Block 2

    Head and Neck

    • Weinstein S, et al. Efficacy and safety of dupilumab in perennial allergic rhinitis and comorbid asthma. JACI
    • Niederberger V, et al. Safety and efficacy of immunotherapy with the recombinant B-cell epitope–based grass pollen vaccine BM32. JACI
    • Ta LDH, et al. Establishment of the nasal microbiota in the first 18 months of life: Correlation with early-onset rhinitis and wheezing. JACI

    Dermatologic

    • Maurer M, Fluhr J, Khan D. How to Approach Chronic Inducible Urticaria. JACI in Practice
    • AygörenPürsün E, et al. Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema. NEJM
    • Fonacier L, Noor I. Contact dermatitis and patch testing for the allergist. Annals

    Lung

    • Dekhuijzen R, et al. Addressing the Impact and Unmet Needs of Nonadherence in Asthma and Chronic Obstructive Pulmonary Disease: Where Do We Go From Here? JACI in Practice
    • Chipps B, et al. The pediatric asthma yardstick Practical recommendations for a sustained step-up in asthma therapy for children with inadequately controlled asthma. Annals
    • Jackson DJ, et al. Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations. NEJM

    Food and Drug Allergy/Hypersensitivity Reactions

    • Kuyucu S, Caubet J-C. Hypersensitivity Reactions to Antiepileptic Drugs in Children: Epidemiologic, Pathogenetic, Clinical, and Diagnostic Aspects. JACI in Practice
    • Macy E, Vyles D. Who needs penicillin allergy testing? Annals
    • Schuyler A, et al. Specific IgG4 antibodies to cow’s milk proteins in pediatric patients with eosinophilic esophagitis. JACI

    Anaphylaxis

    • Carter M, et al. A distinct biomolecular profile identifies monoclonal mast cell disorders in patients with idiopathic anaphylaxis. JACI
    • Wright C, et al. An analysis of anaphylaxis cases at a single pediatric emergency department during a 1-year period. Annals
    • Bonadonna P, et al. Anaphylactic Reactions After Discontinuation of Hymenoptera Venom Immunotherapy: A Clonal Mast Cell Disorder Should Be Suspected. JACI in Practice
    • Motosue M, et al. Outcomes of Emergency Department Anaphylaxis Visits from 2005 to 2014. JACI in Practice

    Hypersensitivity Disorders

    • De Benedetti F, et al. Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes. NEJM
    • Wechsler ME, et al. Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis. NEJM
    • Isabwe G, et al. Hypersensitivity reactions to therapeutic monoclonal antibodies: Phenotypes and endotypes. JACI

    Immunodeficiencies

    • Hajjar J, et al. Questioning the accuracy of currently available pneumococcal antibody testing. JACI
    • Mayor P, et al. Cancer in primary immunodeficiency diseases: Cancer incidence in the United States Immune Deficiency Network Registry. JACI
    • Bonilla F. Update: Vaccines in primary immunodeficiency. Journal of Allergy and Clinical Immunology. JACI

    Eosinophilic and Gastrointestinal Disorders

    • Khoury P, et al. Hypereosinophilic Syndrome Subtype Predicts Responsiveness to Glucocorticoids. JACI in Practice
    • Barbosa A, et al. Eosinophilic Esophagitis: Latent Disease in Patients with Anaphylactic Reaction to Cow’s Milk. JACI in Practice
    • Wechsler J, Hirano I. Biological therapies for eosinophilic gastrointestinal diseases. JACI
  • CAP Articles - 2019 Block 1

    Head and Neck

    • Ellis A, et al. Lack of effect of Timothy grass pollen sublingual immunotherapy tablet on birch pollen–induced allergic rhinoconjunctivitis in an environmental exposure unit. Annals
    • Bachert C, et al. Reduced need for surgery in severe nasal polyposis with mepolizumab: Randomized trial. JACI
    • Chang E, et al. Early life risk factors for chronic sinusitis: A longitudinal birth cohort study. JACI

    Dermatologic

    • Hamad A, Jithpratuck W, Krishnaswamy G. Urticarial vasculitis and associated disorders. Annals
    • Czarnowicki T, et al. Novel concepts of prevention and treatment of atopic dermatitis through barrier and immune manipulations with implications for the atopic march. JACI
    • Yosipovitch G, et al. Serlopitant for the treatment of chronic pruritus: Results of a randomized, multicenter, placebo-controlled phase 2 clinical trial. JAAD

    Lung

    • Dicker A, et al. Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease. JACI
    • Mukherjee M, et al. Sputum autoantibodies in patients with severe eosinophilic asthma. JACI
    • Desai M, Oppenheimer J, Tashkin D. Asthma-chronic obstructive pulmonary disease overlap syndrome What we know and what we need to find out. Annals

    Food and Drug Allergy/Hypersensitivity Reactions

    • Santos A, Brough H. Making the Most of In Vitro Tests to Diagnose Food Allergy. JACI in Practice
    • Sampson H, et al. Effect of Varying Doses of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Exposure Among Patients With Peanut Sensitivity. JAMA
    • Ierodiakonou D, et al. Timing of Allergenic Food Introduction to the Infant Diet and Risk of Allergic or Autoimmune Disease. JAMA

    Anaphylaxis

    • Lieberman P, et al. Anaphylaxis associated with omalizumab administration: Risk factors and patient characteristics. JACI
    • Lee S, et al. Trends, characteristics, and incidence of anaphylaxis in 2001-2010: A population-based study. JACI
    • Buka R, et al. Anaphylaxis and Clinical Utility of Real-World Measurement of Acute Serum Tryptase in UK Emergency Departments. JACI

    Hypersensitivity Disorders

    • Steri M, et al. Overexpression of the Cytokine BAFF and Autoimmunity Risk. NEJM
    • Cunningham A.L., et al. Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older. NEJM
    • Johnson D, et al. Fulminant Myocarditis with Combination Immune Checkpoint Blockade. NEJM

    Immunodeficiencies

    • Banerji A, et al. Inhibiting Plasma Kallikrein for Hereditary Angioedema Prophylaxis. NEJM
    • Monach P, et al. Case 6-2017: A 57-Year-Old Woman with Fatigue, Sweats, Weight Loss, Headache, and Skin Lesions. NEJM
    • De la Morena MT, et al. Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation. JACI

    Eosinophilic and Gastrointestinal Disorders

    • O'Sullivan J, Bochner B. Eosinophils and eosinophil-associated diseases: An update. JACI
    • Spergel J, Aceves S. Allergic components of eosinophilic esophagitis. JACI
    • Kuang F, Klion A. Biologic Agents for the Treatment of Hypereosinophilic Syndromes. JACI in Practice
  • CAP Articles - 2018 Block 2

    Head and Neck

    • Campbell AP, et al. Depression symptoms and lost productivity in chronic rhinosinusitis. Annals
    • Hui JW, et al. Risk of obstructive sleep apnea in African American patients with chronic rhinosinusitis. Annals
    • Stevens WW, et al. Clinical Characteristics of Patients with Chronic Rhinosinusitis with Nasal Polyps, Asthma, and Aspirin-Exacerbated Respiratory Disease. JACI in Practice

    Dermatologic

    • Druey KM, Parikh SM. Idiopathic systemic capillary leak syndrome (Clarkson disease). JACI
    • Fonacier L. A Practical Guide to Patch Testing. JACI in Practice
    • Paller AS, Kabashima K, Bieber T. Therapeutic pipeline for atopic dermatitis: End of the drought? JACI

    Lung

    • Corren J, et al. Tezepelumab in Adults with Uncontrolled Asthma. NEJM
    • Guilbert TW, et al. Real-Life Outcomes for Patients with Asthma Prescribed Spacers for Use with Either Extrafine- or Fine-Particle Inhaled Corticosteroids. JACI in Practice
    • Nair P, et al. Oral Glucocorticoid–Sparing Effect of Benralizumab in Severe Asthma. NEJM

    Food and Drug Allergy/Hypersensitivity Reactions

    • Coop CA, Schapira RS, Freeman TM. Are ACE Inhibitors and Beta-blockers Dangerous in Patients at Risk for Anaphylaxis? JACI in Practice
    • Jones SM, Burks AW. Food Allergy. NEJM
    • Vickery BP, et al. Early oral immunotherapy in peanut-allergic preschool children is safe and highly effective. JACI

    Anaphylaxis

    • Castells, M. Diagnosis and management of anaphylaxis in precision medicine. JACI
    • Feldweg AM. Food-Dependent, Exercise-Induced Anaphylaxis: Diagnosis and Management in the Outpatient Setting. JACI in Practice
    • Motosue MS, et al. Risk factors for severe anaphylaxis in the United States. Annals

    Hypersensitivity Disorders

    • Allenspach E, Torgerson TR. Autoimmunity and Primary Immunodeficiency Disorders. J Clin Immunol
    • Andersen YMF, et al. Autoimmune diseases in adults with atopic dermatitis. JAAD
    • Kanneganti T-D. Inflammatory Bowel Disease and the NLRP3 Inflammasome. NEJM

    Immunodeficiencies

    • Sullivan KE, et al. Emerging Infections and Pertinent Infections Related to Travel for Patients with Primary Immunodeficiencies. J Clin Immunol
    • Walter JE, et al. Mechanism-Based Strategies for the Management of Autoimmunity and Immune Dysregulation in Primary Immunodeficiencies. JACI in Practice
    • Wirsum C, et al. Secondary Antibody Deficiency in Glucocorticoid Therapy Clearly Differs from Primary Antibody Deficiency. J Clin Immunol

    Eosinophilic and Gastrointestinal Disorders

    • Chen Y-YK, et al. Marked and persistent eosinophilia in the absence of clinical manifestations. JACI
    • Molina-Infante J, et al. Step-up empiric elimination diet for pediatric and adult eosinophilic esophagitis: The 2-4-6 study. JACI
    • Pannaraj PS, et al. Association Between Breast Milk Bacterial Communities and Establishment and Development of the Infant Gut Microbiome. JAMA Pediatrics
  • CAP Articles - 2018 Block 1

    Head and Neck

    • Li JT, et al. Sublingual grass and ragweed immunotherapy: Clinical considerations-a PRACTALL consensus report. JACI
    • Bachert, C. Effect of subcutaneous dupilumab on nasal polyp burden in patients with chronic sinusitis and nasal polyposis. JAMA
    • Berard A, et al. Intranasal triamcinolone use during pregnancy and the risk of adverse pregnancy outcomes. JACI

    Dermatologic

    • Nomura, T. Advances in Atopic Dermatitis. JACI
    • Fonacier L, et al. Contact Dermatitis: A Practice Parameter-Update 2015. JACI in Practice
    • Simpson EL, et al. Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis. NEJM

    Lung

    • Virchow, et al. Efficacy of House Dust Mite Sublingual Allergen Immunotherapy Tablet in Adults with Allergic Rhinitis. JAMA
    • Berry, A. Biomarkers in asthmatic patients: Has their time come to direct treatment? JACI
    • Bowatte, G. Traffic-related air pollution exposure is associated with allergic sensitization, asthma, and poor lung function in middle age. JACI

    Food and Drug Allergy/Hypersensitivity Reactions

    • Wood, RA. Food allergen immunotherapy: Current status and prospects for the future. JACI
    • Perkin MR, et al. Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants. NEJM
    • Togias, Alkis. Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases sponsored expert panel. Annals

    Anaphylaxis

    • Golden, et al. Stinging insect hypersensitivity: A practice parameter update 2016. Annals
    • Lieberman, P., et al. Anaphylaxis – a practice parameter update 2015. Annals
    • De Schryver, S, et al. Tryptase levels in children presenting with anaphylaxis: Temporal trends and associated factors. JACI

    Hypersensitivity Disorders

    • Her, M. Alterations in immune function with biologic therapies for autoimmune disease. JACI
    • Green, PHR. Celiac Disease. JACI
    • Hoffman, HM. The role of the inflammasome in patients with autoinflammatory diseases. JACI

    Immunodeficiencies

    • Gudmundsdottir, Judith. Early thymectomy leads to premature immunologic ageing: An 18-year follow-up. JACI
    • Loffredo L, et al. Chronic granulomatous disease as an SOS call for multicenter cooperative effort to prevent infections. Annals
    • Bonilla, FA. Practice parameter for the diagnosis and management of primary immunodeficiency. JACI

    Eosinophilic and Gastrointestinal Disorders

    • Williams KW, et al. Hypereosinophilia in Children and Adults: a retrospective comparison. JACI in Practice
    • Blumenthal KG, et al. Peripheral blood eosinophilia and hypersensitivity reactions among patients receiving outpatient parenteral antibiotics. JACI
    • Furuta, GT. Eosinophilic Esophagitis. NEJM